Welcome to the Urethral Stricture Support blog. These pages are intended to assist those with questions regarding the disease, expected outcomes, resources, and emotional and informational support. AT NO TIME WILL MEDICAL ADVICE OF ANY KIND BE RENDERED. With your permission, your commentary may be included within the topics discussed within this forum. Moderators Cesar and Tim have a combined 50 years (celebrating a half-century of difficult urination) of experience in living with, dealing with, and overcoming what is broadly considered a disease with a high rate of morbidity. We have experienced every common surgical and instrumental "fix"/"repair" offered including the implantation of the Urolume Endoprosthesis. Both moderators have experience with the Urolume Endoprosthesis. To the best of our knowledge, this is the first and only such support group anywhere. Please, do not be afraid or embarrassed to ask any question with regards to your diagnosis. We encourage you to discuss any and all information offered within this blog with your Urologist. A proactive and informed patient usually receives the best care.

With your help, and well-considered posts, the information gleaned from this site should help the countless scores of males aged 18 and over who are encountering the diagnosis of "Urethral Stricture".


DISCLAIMER: We do not provide medical advice. We disseminate information relevant to urethral stricture disease. While we encourage research (and participation in research), we endorse no medication or treatment protocols. PLEASE FEEL FREE TO CONTACT US WITH SPECIFIC QUESTIONS @ urethralstrictures[no spam] at yahoo dot com

Tuesday, July 17, 2012

Bioengineered Urethral Tissue, quite possibly our greatest hope for a return to normal life...

A little more than a year ago, Time Magazine published an article entitled "Scientists Grow New Body Parts in the Lab".  Low and behold, the article was about a team at Wake Forest University's research into creating human urethral tissue which is grown on a tubular "scaffolding", and suitable for transplant into human males with strictures which would otherwise have probably required a partial urostomy, or Johansen's Urethroplasty to achieve urinary drainage.

The research team, led by Dr. Anthony Atala, director of the Wake Forest Institute of Regenerative Medicine created the human urethras (trust me, this was no easy process!) and transplanted them into a total of five young men, the most recent, in 2010. The longest-term recipients, all young boys have successfully retained the bioengineered tissue, which functions identically to their own (and seems to have become almost indistinguishable from their own urethral tissue), for a period of time approaching six years. Adult subjects have not taken part in this research, thus far - but I can guarantee that there will be no shortage of volunteers!!

My writing more will not do the subject the justice it deserves, here's a link to **"The Lancet" research paper. It is in .pdf format: http://www.mediafire.com/?3jdiyp8tlf3op3w

** © The Lancet, 2011, and respective research copyrights,

**© The Wake Forest Institute of Regenerative Medicine and Dr. Anthony Atala,

Our thanks to "Dr. Joe", our resident urologist, and an editor for WikiProject- Medicine©, whose work on updating this site, and that of Wikipedia's "reconstructive urology" pages is to be commended,

Many thanks to "Karen", of the Wake Forest Institute of Regenerative Medicine, who provided this info for all to see, and was instrumental in procuring the document for "Dr. Joe". Should you ever visit central Pennsylvania, I owe you a steak dinner!


Per: Moderator Tim

No comments:

Post a Comment